Equine Lactate Calculator

Please note any results presented here should not be a sole decision maker in colic cases

Input Values

Blood Lactate: Peritoneal Lactate:

Results

Summary Information

Blood Lactate: Lactate levels in the blood can indicate circulatory shock, hypoxaemia and anaemia or decreased lactate clearance.

Peritoneal Lactate: Elevated peritoneal lactate can indicate strangulated bowel, peritonitis, enteritis and colitis.

Lactate Ratio: The ratio of peritoneal lactate to blood lactate can help in assessing the severity and origin of lactate production, providing valuable diagnostic information.

Surgery Recommendation: A higher probability indicates a stronger recommendation for surgical intervention based on lactate levels and ratios.

Survival to Discharge: Probability estimation of survival to discharge based on the provided lactate values and calculated ratios.

Legend:

* Above cut point for surgery

^ Above cut point for survival

*^ Above cut points for both surgery and survival

Statistics

Sensitivity and Specificity (Peritoneal Lactate and Surgery): 71% sensitivity, 72% specificity, Cut Point: 8 mmol/L, AUROC: 0.75

Sensitivity and Specificity (Peritoneal Lactate and Survival): 77% sensitivity, 81% specificity, Cut Point: 5.2 mmol/L, AUROC: 0.86

Sensitivity and Specificity (Lactate Ratio and Surgery): 71% sensitivity, 66% specificity, Cut Point: 2.5, AUROC: 0.76

Sensitivity and Specificity (Lactate Ratio and Survival): 75% sensitivity, 81% specificity, Cut Point: 2.36, AUROC: 0.77

Bibliography

These are some relevant references related to prognosticating colic with lactate. Here are some references:

Latson, K.M., Nieto, J.E., Beldomenico, P.M. and Snyder, J.R., 'Evaluation of peritoneal fluid lactate as a marker of intestinal ischaemia in equine colic', Equine Veterinary Journal, 37.4 (2005), 342-6. https://beva.onlinelibrary.wiley.com/doi/abs/10.2746/0425164054529319
Henderson, I.S.F., 'Diagnostic and prognostic use of L‐lactate measurement in equine practice', Equine Veterinary Education, 25.9 (2012), 468-475. https://beva.onlinelibrary.wiley.com/doi/10.1111/eve.12033
Van den Boom, R., Butler, C.M. and Sloet van Oldruitenborgh‐Oosterbaan, M.M., 'The usability of peritoneal lactate concentration as a prognostic marker in horses with severe colic admitted to a veterinary teaching hospital.', Equine Veterinary Education, 22.8 (2010), 420-5. https://beva.onlinelibrary.wiley.com/doi/10.1111/j.2042-3292.2010.00093.x
Bishop, R.C., Gutierrez‐Nibeyro, S.D., Stewart, M.C. and McCoy, A.M., 'Performance of predictive models of survival in horses undergoing emergency exploratory laparotomy for colic', Veterinary Surgery, 51.6 (2022), 891-902. https://onlinelibrary.wiley.com/doi/10.1111/vsu.13839

Lactate Prognostication Calculator

Input Values

Results

Summary Information

Statistics

Bibliography